Extreme heat and pediatric health in a warming world: a space-time stratified case-crossover investigation in Ontario, Canada
Bush E, Flato G. Canada’s Changing Climate Report. Ottawa, Ontario; 2019.
Communicating the Health Risks of Extreme Heat. Events — Canada.ca [Internet]. [cited 2021 May 1]. Available from: https://www.canada.ca/en/health-canada/services/environmental-workplace-health/reports-publications/climate-change-health/communicating-health-risks-extreme-heat-events-toolkit-public-health-emergency-management-officials-health-canada-2011.html
Environmental Protection Agency U. Excessive Heat Events Guidebook. 2006.
Criteria for public. weather alerts — Canada.ca [Internet]. [cited 2020 Nov 25]. Available from: https://www.canada.ca/en/environment-climate-change/services/types-weather-forecasts-use/public/criteria-alerts.html
Heat. and Health [Internet]. [cited 2022 Oct 26]. Available from: https://www.who.int/news-room/fact-sheets/detail/climate-change-heat-and-health
Luber G, McGeehin M. Climate Change and Extreme Heat events. Am J Prev Med Elsevier; Nov. 2008;1:429–35.
Sun S, Weinberger KR, Nori-Sarma A, Spangler KR, Sun Y, Dominici F, et al. Ambient heat and risks of emergency department visits among adults in the United States: Time stratified case crossover study. BMJ. 2021;375:1–12.
Bishop-Williams KE, Berke O, Pearl DL, Kelton DF. A spatial analysis of heat stress related emergency room visits in rural Southern Ontario during heat waves. BMC Emerg Med. 2015;15(1).
Colombo AF, Etkin D, Karney BW. Climate Variability and the frequency of Extreme temperature events for Nine sites across Canada: implications for power usage. J Clim. 1999;12(8):2490–502.
Wu J, Yunus M, Ali M, Escamilla V, Emch M. Influences of heatwave, rainfall, and tree cover on cholera in Bangladesh. Environ Int. 2018;120:304–11.
Xu Z, Sheffield PE, Su H, Wang X, Bi Y, Tong S. The impact of heat waves on children’s health: a systematic review. Int J Biometeorol. 2014;58(2):239–47.
Dover G, Eagan P, Gould R, Hayes J, Kenny GP, Moore K et al. Extreme Heat Events Guidelines: Technical Guide for Health Care Workers — Canada.ca [Internet]. 2011 [cited 2020 Nov 25]. Available from: https://www.canada.ca/en/health-canada/services/environmental-workplace-health/reports-publications/climate-change-health/extreme-heat-events-guidelines-technical-guide-health-care-workers.html#ref279
Baker LB, Barnes KA, Anderson ML, Passe DH, Stofan JR. Normative data for regional sweat sodium concentration and whole-body sweating rate in athletes. J Sports Sci. 2016;34(4):358–68.
Chauvin M, Kosatsky T, Bilodeau-Bertrand M, Gamache P, Smargiassi A, Auger N. Hot weather and risk of drowning in children: opportunity for prevention. Prev Med (Baltim). 2020:130.
Wilk P, Gunz A, Maltby A, Ravichakaravarthy T, Clemens KK, Lavigne É, et al. Extreme heat and paediatric emergency department visits in Southwestern Ontario. Paediatr Child Heal. 2021;26(5):305–9.
Kyselý J, Kim J. Mortality during heat waves in South Korea, 1991 to 2005: how exceptional was the 1994 heat wave? Clim Res. 2009;38(2):105–16.
Knowlton K, Rotkin-Ellman M, King G, Margolis HG, Smith D, Solomon G, et al. The 2006 California Heat Wave: impacts on hospitalizations and Emergency Department visits. Environ Health Perspect. 2009;117(1):61.
Bernstein AS, Sun S, Weinberger KR, Spangler KR, Sheffield PE, Wellenius GA. Warm season and Emergency Department visits to U.S. children’s hospitals. Environ Health Perspect. 2022;130(1):17001.
Leonardi GS, Hajat S, Kovats RS, Smith GE, Cooper D, Gerard E. Syndromic surveillance use to detect the early effects of heat-waves: an analysis of NHS direct data in England. Sozial- Und Präventivmedizin 2006 514. 2006;51(4):194–201.
Forward Sortation Area—Definition [Internet]. [cited 2023 Jun 4]. Available from: https://ised-isde.canada.ca/site/office-superintendent-bankruptcy/en/statistics-and-research/forward-sortation-area-fsa-and-north-american-industry-classification-naics-reports/forward-sortation-area-definition
Uibel D, Sharma R, Piontkowski D, Sheffield PE, Clougherty JE. Association of ambient extreme heat with pediatric morbidity: a scoping review. Int J Biometeorol. 2022;66(8).
Kovats RS, Hajat S, Wilkinson P. Contrasting patterns of mortality and hospital admissions during hot weather and heat waves in Greater London. UK. 2004;61(11):893–8.
Nitschke M, Tucker GR, Bi P. Morbidity and mortality during heatwaves in metropolitan Adelaide. Med J Aust. 2007;187(11–12):662–5.
Figgs LW. Emergency department asthma diagnosis risk associated with the 2012 heat wave and drought in Douglas County NE, USA. Hear Lung. 2019;48(3):250–7.
Nitschke M, Tucker GR, Hansen AL, Williams S, Zhang Y, Bi P. Impact of two recent extreme heat episodes on morbidity and mortality in Adelaide, South Australia: a case-series analysis. Environ Heal Glob Access Sci Source. 2011;10(1):1–9.
ICD-10-CA/CCI. Implementation Schedule | CIHI [Internet]. [cited 2024 May 10]. Available from: https://www.cihi.ca/en/icd-10-cacci-implementation-schedule
Xu Z, Crooks JL, Black D, Hu W, Tong S. Heatwave and infants’ hospital admissions under different heatwave definitions. Environ Pollut. 2017;229:525–30.
Xiao J, Spicer T, Jian L, Yun GY, Shao C, Nairn J, et al. Variation in Population vulnerability to heat Wave in Western Australia. Front Public Heal. 2017;5(APR):64.
Sohail H, Lanki T, Kollanus V, Tiittanen P, Schneider A. Heat, heatwaves and Cardiorespiratory Hospital Admissions in Helsinki, Finland. Int J Environ Res Public Health. 2020;17(21):1–11.
Wang X, Lavigne E, Ouellette-Kuntz H, Chen BE. Acute impacts of extreme temperature exposure on emergency room admissions related to mental and behavior disorders in Toronto, Canada. J Affect Disord. 2014;155(1):154–61.
Weinberger KR, Zanobetti A, Schwartz J, Wellenius GA. Effectiveness of National Weather Service heat alerts in preventing mortality in 20 US cities. Environ Int. 2018;116:30–8.
Khalaj B, Lloyd G, Sheppeard V, Dear K. The health impacts of heat waves in five regions of New South Wales, Australia: a case-only analysis. Int Arch Occup Environ Health. 2010;83(7):833–42.
Wilson LA, Gerard Morgan G, Hanigan IC, Johnston FH, Abu-Rayya H, Broome R, et al. The impact of heat on mortality and morbidity in the Greater Metropolitan Sydney Region: a case crossover analysis Leigh. Environ Heal. 2013;12(1):98.
Winquist A, Grundstein A, Chang HH, Hess J, Sarnat SE. Warm season temperatures and emergency department visits in Atlanta, Georgia. Environ Res. 2016;147:314–23.
Wang X-YY, Barnett A, Guo Y-MM, Yu W-WW, Shen X-MM, Tong S-LL. Increased risk of emergency hospital admissions for children with renal diseases during heatwaves in Brisbane, Australia. World J Pediatr. 2014;10(4):330–5.
Alsaiqali M, De Troeyer K, Casas L, Hamdi R, Faes C, Van Pottelbergh G. The effects of heatwaves on Human Morbidity in Primary Care settings: a case-crossover study. Int J Environ Res Public Health. 2022;19(2):832.
Soneja S, Jiang C, Fisher J, Upperman CR, Mitchell C, Sapkota A. Exposure to extreme heat and precipitation events associated with increased risk of hospitalization for asthma in Maryland, U.S.A. Environ Heal A Glob Access. Sci Source. 2016;15(1):1–7.
Zhang A, Hu W, Li J, Wei R, Lin J, Ma W. Impact of heatwaves on daily outpatient visits of respiratory disease: a time-stratified case-crossover study. Environ Res. 2019;169:196–205.
Xu Z, Huang C, Hu W, Turner LR, Su H, Tong S. Extreme temperatures and emergency department admissions for childhood asthma in Brisbane, Australia. Occup Environ Med. 2013;70(10):730–5.
Armstrong BG, Gasparrini A, Tobias A. Conditional Poisson models: a flexible alternative to conditional logistic case cross-over analysis. BMC Med Res Methodol. 2014;14(1).
Wu Y, Li S, Guo Y. Space-Time-Stratified Case-Crossover Design in Environmental Epidemiology Study. Heal Data Sci. 2021;2021.
Jaakkola JJK. Case-crossover design in air pollution epidemiology. Supplement: In: European Respiratory Journal; 2003.
Janes H, Sheppard L, Lumley T. Case-crossover analyses of air pollution exposure data: Referent selection strategies and their implications for bias. Vol. 16, Epidemiology. Epidemiology; 2005. pp. 717–26.
Xu R, Xiong X, Abramson MJ, Li S, Guo Y. Ambient temperature and intentional homicide: a multi-city case-crossover study in the US. Environ Int. 2020;143(June):105992.
Janes H, Sheppard L, Lumley T. Overlap bias in the case-crossover design, with application to air pollution exposures. Stat Med Stat Med. 2005;24:285–300.
Côté J-N. DayMet data extraction methodology. 2022.
QGIS. Welcome to the QGIS project [Internet]. QGIS Geographic Information System. Open Source Geospatial Foundation Project. 2022 [cited 2022 Sep 26]. Available from: https://qgis.org/en/site/
Gorelick N, Hancher M, Dixon M, Ilyushchenko S, Thau D, Moore R. Google Earth Engine: planetary-scale geospatial analysis for everyone. Remote Sens Environ. 2017;202:18–27.
Statistics Canada. Population Ecumene Census Division, Cartographic Boundary files – 2016 Census. 2016;(92).
Turner H, Firth D. Generalized nonlinear models in R: An overview of the gnm package [Internet]. 2022 [cited 2023 Jun 4]. Available from: https://cran.r-project.org/package=gnm
van Loenhout JAF, Delbiso TD, Kiriliouk A, Rodriguez-Llanes JM, Segers J, Guha-Sapir D, et al. Heat and emergency room admissions in the Netherlands. BMC Public Health. 2018;18(1):108.
Girma B, Liu B, Schinasi LH, Clougherty JE, Sheffield PE. High ambient temperatures associations with children and young adult injury emergency department visits in NYC. Environ Res Heal. 2023;1(3):035004.
Sheffield PE, Herrera MT, Kinnee EJ, Clougherty JE. Not so little differences: variation in hot weather risk to young children in New York City. Public Health. 2018;161:119–26.
Parsons N, Odumenya M, Edwards A, Lecky F, Pattison G. Modelling the effects of the weather on admissions to UK trauma units: a cross-sectional study. Emerg Med J. 2011;28(10):851–5.
Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson MA, Roy SL, et al. Foodborne Illness Acquired in the United States—Major pathogens — 17, number 1—January 2011 — emerging infectious diseases journal — CDC. Emerg Infect Dis. 2011;17(1):7–15.
Salmonellosis N. | CDC Yellow Book 2024 [Internet]. [cited 2024 Jun 14]. Available from: https://wwwnc.cdc.gov/travel/yellowbook/2024/infections-diseases/salmonellosis-nontyphoidal
Norovirus | CDC Yellow. Book 2024 [Internet]. [cited 2024 Jun 14]. Available from: https://wwwnc.cdc.gov/travel/yellowbook/2024/infections-diseases/norovirus
Campylobacteriosis | CDC Yellow. Book 2024 [Internet]. [cited 2024 Jun 14]. Available from: https://wwwnc.cdc.gov/travel/yellowbook/2024/infections-diseases/campylobacteriosis
van der Linden N, Longden T, Richards JR, Khursheed M, Goddijn WMT, van Veelen MJ et al. The use of an acclimatisation heatwave measure to compare temperature-related demand for emergency services in Australia, Botswana, Netherlands, Pakistan, and USA. PLoS ONE. 2019;14(3).
Tobías A, Madaniyazi L, Gasparrini A, Armstrong B. High summer temperatures and heat stroke mortality in Spain. Epidemiology. 2023;34(6):892–6.
Colonna KJ, Alahmad B, Choma EF, Albahar S, Al-Hemoud A, Kinney PL, et al. Acute exposure to total and source-specific ambient fine particulate matter and risk of respiratory disease hospitalization in Kuwait. Environ Res. 2023;237:117070.
Htay ZW, Ng CFS, Kim Y, Lim YH, Iwagami M, Hashizume M. Associations between short-term exposure to ambient temperature and renal disease mortality in Japan during 1979–2019. Environ Epidemiol. 2024;8(1):E293.
Lu P, Xia G, Zhao Q, Green D, Lim YH, Li S, et al. Attributable risks of hospitalizations for urologic diseases due to heat exposure in Queensland, Australia, 1995–2016. Int J Epidemiol. 2022;51(1):144–54.
Kubo R, Ueda K, Seposo X, Honda A, Takano H. Association between ambient temperature and intentional injuries: a case-crossover analysis using ambulance transport records in Japan. Sci Total Environ. 2021;774:145511.
Huang W, Li S, Vogt T, Xu R, Tong S, Molina T, et al. Global short-term mortality risk and burden associated with tropical cyclones from 1980 to 2019: a multi-country time-series study. Lancet Planet Heal. 2023;7(8):e694–705.
Ingole V, Sheridan SC, Juvekar S, Achebak H, Moraga P. Mortality risk attributable to high and low ambient temperature in Pune city, India: a time series analysis from 2004 to 2012. Environ Res. 2022;204:112304.
Stowell JD, Sun Y, Spangler KR, Milando CW, Bernstein AS, Weinberger KR et al. Warm-season temperatures and emergency department visits among children with health insurance. Environ Res Heal. 2022:1.
Gemmell E, Adjei-Boadi D, Sarkar A, Shoari N, White K, Zdero S, et al. In small places, close to home: urban environmental impacts on child rights across four global cities. Health Place. 2023;83:103081.
Census Profile [Internet]. [cited 2023 Feb 26]. Available from: https://www12.statcan.gc.ca/census-recensement/2011/dp-pd/prof/index.cfm?Lang=E&TABID=2
Kassem H. A case-crossover investigation of associations between extreme heat and pediatric health. 2023.